Shrines that have not yet been unlocked glow an orange light, and glow orange and blue once their entrance has been opened, but not yet completed. In order to enter an Ancient Shrine, Link must unlock the entrance by pressing his Sheikah Slate to the Sheikah Slate Terminal at a Shrine's entrance. Many of the Ancient Shrines where uncovered during King Rhoam's excavations for Ancient Technology, but they only began to glow after Link activated the Great Plateau Tower following his Slumber of Restoration. There are initially 120 Ancient Shrines scattered throughout Hyrule Kingdom.
After the Sheikah helped to seal away Calamity Ganon, they built the Ancient Shrines to serve as training grounds for the hero as he prepared for the revival of Calamity Ganon.